A Web Server for Multiple Sequence Alignment Using Genetic Algorithm

So far, many multiple alignment algorithms have been developed and applied to an extensive area of the genome sequences analysis. Genetic algorithm (GA) is one of such algorithms and it has been successfully applied to multiple alignment methods. As pointed out in the paper in which many multiple alignment programs have been assessed, GA is one of the most reliable approaches to align multiple sequences [5]. For these years, we have developed an original code of Multiple sequence Alignment using GA (we call this program MAGA [1, 2, 3]) and have constructed a web server for the easy use of the program through a simple interface. Within our knowledge, there has been no multiple alignment web server utilizing GA. The MAGA web server is available from the web site, http://sci.hirosakiu.ac.jp/ infobio/index.html.